Saint Syagrius (French: Saint-Siacre; died 600 AD) was a bishop of Autun.
He was bishop of Autun from around 560 until his death and travelled to Nanterre with Guntram for the baptism of Chlothar II.
Pope Gregory I granted Syagrius the pallium and decreed that the bishops of Autun have precedence in France after the archbishop of Lyon.
Syagrius was son of Bishop (later Saint) Desideratus of Verdun, who was killed by Sirivald, for reasons of rivalry and revenge.
Syagrius organized a punitive expedition in 554, to assassinate Sirivald in a villa, after murdering a first person by mistake, they returned to fulfil its mission.