It is in North Central Arizona bordering and below the Mogollon Rim, and is located west and northwest of Sedona in Yavapai and Coconino counties.

Sycamore Creek, a tributary of the Verde River, flows through the canyon.

[1] Located within three different U.S. National Forests, the Coconino, Kaibab, and Prescott National Forests, Sycamore Canyon is home to a variety of wildlife including black bear, deer, and mountain lion.

Hiking and horseback riding are the only ways to visit the canyon.

The most popular access is via the Parsons Spring trail, upriver from Tuzigoot National Monument.