[7] Le Touzel appeared in various television productions throughout the 1990s, including the police procedural Between the Lines (1994), an adaptation of Catherine Cookson's The Gambling Man (1995), and the science fiction miniseries The Uninvited (1997).

Later credits included prominent roles in the Victoria Wood television film Housewife, 49 (2004), political drama series The Amazing Mrs Pritchard (2006), an adaptation of Jane Austen's Northanger Abbey (2007), the ITV comedy-drama series Bonkers (2007), the BBC Four film Margaret Thatcher: The Long Walk to Finchley (2008)—in which she portrayed Conservative politician Patricia Hornsby-Smith—and the four-part ITV/ABC miniseries Titanic (2012), where she played Lady Duff-Gordon, a survivor of the sinking of the Titanic.

In addition, her work as D.C. Hazel Savage in the two-part television film Appropriate Adult (2011), a dramatisation of the crimes of Fred and Rose West, was described as "very authentic" by Variety and "remarkable" by the Los Angeles Times.

[14] She then co-starred as Heather in Happy-Go-Lucky (2008), a partially improvised comedy-drama directed by Mike Leigh,[15] which The Hollywood Reporter called a "certified good time" with "wonderful performances from top to bottom".

[16] Following a small part in The Iron Lady (2011), Le Touzel played three different characters in Cloud Atlas (2012), a big-budget science fiction drama directed by the Wachowskis.