Two of Boswell's music videos, "A Glorious Dawn" and "We are All Connected", feature appearances from Carl Sagan, Richard Feynman, Neil deGrasse Tyson, Bill Nye, and Stephen Hawking.

[citation needed] On November 9, 2009, Third Man Records released a 7-inch single of "A Glorious Dawn" for the 75th anniversary of the birth of Carl Sagan.

[2][3] Born in Idaho, John Boswell attended Gonzaga Preparatory School[4] and graduated from Western Washington University in 2008 with a degree in economics.

Boswell had worked with Auto-Tune in the past and thought people might be interested in hearing American astronomer Carl Sagan sing.

[13] In addition to Symphony of Science, Boswell is also working on a project called Remixes for the Soul, as well as scientific-based films, most notably Timelapse of the Future, under the moniker Melodysheep.

[11] Boswell's first video in the Symphony of Science series is 3 minutes, 34 seconds long and features Carl Sagan and Stephen Hawking.

On January 23, 2010, the video was shown at the South Nassau Unitarian Universalist Church in Long Island NY, as part of a youth-directed service.

The title comes from the chorus spoken by Neil deGrasse Tyson and remixed by Boswell: The third video in the series is 4 minutes, 21 seconds in length and was released on November 23, 2009.

The title comes from words spoken by Carl Sagan and remixed by Boswell: The fourth video in the series is 4 minutes in length and was released on January 6, 2010.

"The Unbroken Thread" is themed around biology and evolution rather than the cosmos, and features Carl Sagan, David Attenborough, and Jane Goodall.

The fifth installment uses clips from various prominent scientists and speakers - including Jacob Bronowski, Sagan, Feynman, Dawkins, Brian Greene, Stephen Hawking, PZ Myers, Lawrence Krauss, Michael Shermer, and deGrasse Tyson - to explain and promote science, its process, and its benefits.

"[18] The chorus is sung by Dawkins, except for the last line which is Phil Plait's: "The Big Beginning" is the eighth installment in the Symphony of Science music video series, released on January 20, 2011.

The music video features Stephen Hawking, Richard Dawkins, Carl Sagan, Tara Shears, and Neil deGrasse Tyson.

It features Carl Sagan, Robert Winston, Vilayanur Ramachandran, Jill Bolte Taylor, Bill Nye and Oliver Sacks.

It deals with the bizarre discoveries made in the field of quantum mechanics, through "a musical investigation into the nature of atoms and subatomic particles."

It features Morgan Freeman, Stephen Hawking, Michio Kaku, Brian Cox, Richard Feynman, and Frank Close.

Programs sampled for this instalment include Richard Feynman's Fun to Imagine, Morgan Freeman's Through the Wormhole, Brian Cox's TED Talk, along with BBC documentaries Visions of the Future, What Time is it, Wonders of the Universe, and What Is Reality.

"Onward to the Edge," "a musical investigation into the importance and inspirational qualities of space exploration (human and robotic), as well as a look at some of the amazing worlds in our solar system," is the twelfth installment of the Symphony of Science series, released on November 9, 2011.

Programs sampled for this installment include Wonders of the Solar System, My Favorite Universe, A Traveler's Guide to the Planets, and Carolyn Porco's TED Talk.

On September 12, 2012 the sixteenth installment of Symphony of Science, titled "Our Biggest Challenge (Climate Change Music Video)" was released.

It explores the beauty of Einstein's concept of relativity, its applications to time, speed, energy and mass, and its effects on the movement and light of stars.

Michio Kaku performs the chorus with Brian Cox, who sings only the first and fourth lines: On August 27, 2013, the eighteenth installment, titled "Monsters of the Cosmos" was released.

It was created in collaboration with the Planetary Society, and is sung by Bill Nye, Neil deGrasse Tyson, Emily Lakdawalla, and Carl Sagan.

On December 10, 2018, the twenty-second installment of Symphony of Science, titled "Children of Planet Earth: The Voyager Golden Record Remixed" was released.

The music video ends with a Morse code message spelling out Per aspera ad astra, meaning "Through hardships to the stars."

In addition to the four presenters - Liz Bonnin, Dallas Campbell, Jem Stansfield, and Yan Wong - there are guest spots for Jim Al-Khalili and Tara Shears.

While not strictly part of the Symphony of Science series, Boswell uses the same formula of pitch correction of spoken words over an original music track.

"[25] Columnist Franklin Harris argues that Boswell's videos show that science can arouse the minds of artists just as much as religion and mythology have in the past.

Christopher Jion, of Dirgefunk Records, has praised Symphony of Science saying, "When I first heard John Boswell's "A Glorious Dawn," it brought tears to my eyes, it was life-changing.