Synthetic Sin is a 1929 American sound comedy film directed by William A. Seiter, based on a play of the same name.

[1] While the film has no audible dialog, it was released with a synchronized musical score with sound effects using both the sound-on-disc and sound-on-film process.

Famed playwright Donald Anthony returns home to Magnolia Gap, Virginia, and proposes to Betty Fairfax.

The film featured a theme song entitled "Betty" which was composed by Nathaniel Shilkret and Harold Christy.

Colleen Moore had deposited copies of several of her movies with the Museum of Modern Art (MOMA), but it allowed the films to decompose before they could be restored.