Saint Syrus of Genoa (Italian: San Siro di Genova) (died around June 29, 381 AD) was a priest and later bishop of Genoa during the fourth century AD.

As a boy, Saint Syrus is reputed to have brought his pet blackbird back to life by means of his saliva.

Later, walking with his father in the hills above, he wished that a boat making for port might be still, whereupon the wind died and the ship came to a halt as if at anchor.

[2] A legend holds that the bishop was able to banish a basilisk that dwelt in a well adjacent to the Church of the Twelve Apostles; a plaque on a nearby house recalls the miracle.

This event is represented in a medieval bas relief on the portico arcade next to the church, as well as a fresco by Carlone in the apse.