The House of Szécsényi was a noble family of the Kingdom of Hungary in the 14-15th centuries.

The ancestor of the family, Thomas descended from the gens ("clan") Kacsics.

He was one of the most powerful barons of King Charles I of Hungary and he hold several dignities during his reign.

The family was named after its possession, Szécsény.

The male line of the family ended in 1460.