1KZZ, 1L0A1001021353ENSG00000136560ENSMUSG00000064289Q92844Q6NW12P70347NM_001199135NM_004180NM_133484NM_001374667NM_001378922NP_001186064NP_004171NP_597841NP_001186064.1NP_001361596NP_001365851TRAF family member-associated NF-kappa-B activator is a protein that in humans is encoded by the TANK gene.

The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm.

Two transcript variants encoding different isoforms have been found for this gene.

[7] TANK (gene) has been shown to interact with TANK-binding kinase 1,[8][9] IKBKE,[10] TRAF2,[5][8][9][10] IKBKG[11] and TRAF3.

[5][8] This article on a gene on human chromosome 2 is a stub.