Thiosulfate–citrate–bile salts–sucrose agar

Since no yellow bacterial growth is observed in case of Campylobacter species on TCBS agar, chances of incorrect diagnosis can be rectified.

Sodium thiosulfate also serves as a sulfur source and its presence, in combination with ferric citrate, allows for the easy detection of hydrogen sulfide production.

TCBS agar has also been used to control outbreaks of the crown-of-thorns sea star (Acanthaster planci), which is a threat to coral reefs.

Blisters on the dorsal integument broke through the skin surface and resulted in large, open sores that exposed the internal organs."

This was due to promotion of the growth of naturally occurring Vibrio species to high densities, with subsequent symbiont imbalance.

TCBS agar plate of Vibrio cholerae (left) and Vibrio parahaemolyticus (right)
Yellow coloured (sucrose-fermenting) colonies of Vibrio cholerae on TCBS agar.