Tabalumab (LY 2127399) is an anti-B-cell activating factor (BAFF) human monoclonal antibody designed for the treatment of autoimmune diseases and B cell malignancies.
A phase III clinical trial for rheumatoid arthritis was halted in Feb 2013.
[3] In September 2014, a second phase III trial focussing on treating systemic lupus erythematosus, was terminated early as the study failed to meet its primary endpoint.
[4] Immune activation: Dostarlimab Other: Ibalizumab Now dropped by Lilly due to lack of efficacy.
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