Asia Pacific Airlines operates out of Tabubil as its hub.

[2] Air travel was instrumental in the development of the town, as there were no roads and the Kiunga-Tabubil Highway, which was a major logistical problem, was not constructed yet.

Asia Pacific Airlines is a local company with head offices in Tabubil, and Airlines PNG, Mission Aviation Fellowship and Air Niugini also fly to Tabubil Regularly.

Tabubil has a history of poor aircraft safety, and many fatal crashes have occurred in the nearby mountains.

Additionally, due to weather conditions, many aircraft have had to be diverted to Kiunga and passengers transported by road or helicopter for the remainder of the journey.