In 1962, after completing his secondary schooling, he studied at the Department of Physics and Mathematics at the Grodno Pedagogical Institute, a teachers' training college.

On 10 May 1989, Pope John Paul II appointed him Apostolic Administrator of Minsk, Belarus and Titular Bishop of Hippo Diarrhytus.

On 20 October, he was consecrated bishop by John Paul at St. Peter's Basilica,[4] with Cardinals Edward Idris Cassidy and Francesco Colasuonno as co-consecrators.

as a moderate conservative, being hostile towards the traditionalist movement and the restoration of the Tridentine Mass, but at the same time disallowing or discouraging many of the excesses of theological and liturgical liberalism in his diocese.

[citation needed] He has been instrumental in the reestablishment of the Roman Catholic Church in Russia after the collapse of the Communist regime.

[citation needed] On 21 September 2007, Kondrusiewicz was appointed Metropolitan Archbishop of Minsk-Mahilyow by Pope Benedict XVI.

[9] During mass on 1 November 2017, Kondrusiewicz called the 1917 October Revolution in Russia an "existential disaster" that brought immense suffering to Belarus.