He was educated at the Faculty of Philology, History and Geography in Ankara University, graduating 1940.
Following his retirement in 1981, he was five years long in charge of vice chairman of the High Education Council of Turkey.
Ozgüç was the excavator of the famous site of Kültepe (Kayseri), ancient Kanesh, where his 57 years of continuous excavation produced sensational architectural artifacts and texts, revealing in extraordinary detail the first historical period of Anatolia, that of the Assyrian merchant colonies, about 2000–1700 BC.
He also led excavations in Karahöyük Elbistan, Horoztepe (Tokat), Altıntepe (Erzincan), Maşathöyük, Kazankaya and Kululu.
The book paid homage to the importance of the Özgüçs in establishing the field of archaeology in the country.