The western half of the city is reclaimed land and is part of the Sakai Senboku Seaside Industrial Zone.

Osaka Prefecture Takaishi has a Humid subtropical climate (Köppen Cfa) characterized by warm summers and cool winters with light to no snowfall.

During the Russo-Japanese War, a large Prisoner-of-war camp was constructed on the coast of Takaishi, with an area of 430,000 square meters and a capacity to house 28,000 prisoners.

Takaishi has a mayor-council form of government with a directly elected mayor and a unicameral city council of 16 members.

Takaishi collectively with the city of Izumiōtsu and the town of Tadaoka contributes two members to the Osaka Prefectural Assembly.

Takaishi is located in the Sakai Senboku Seaside Industrial Zone, with half the city area on reclaimed land on the coast of Osaka Bay.