Tandamine is a selective norepinephrine reuptake inhibitor with a tricyclic structure.

[1][2][3] It was developed in the 1970s as an antidepressant but was never commercialized.

[1][2][3] Tandamine is analogous to pirandamine, which, instead, acts as a selective serotonin reuptake inhibitor (SSRI).

[4][5] The exact identical same structure, although this time changing the thioether to a methylene group revealed a strongest compound of the series called AY 24614.

[6] This drug article relating to the nervous system is a stub.