On November 30, 1843, Marzio Gaetano Carafa, principle of Colubrano, sold the theatre to Enrico del Prete, who then sublet it to Adamo Alberti (1809–1885), comedian and impresario of the Teatro dei Fiorentini.
[4] Golia and his wife Raffaella Salvatore Bartolomeo (sister of Louis), became the sole owners of the theatre, and he entrusted the management to his son Giuseppe.
Golia sold the ruins to De Filippo on February 25, 1948, who invested in the reconstruction of the theatre with his earnings from his movies,[10] and with bank loans, forming his Il Teatro di Eduardo.
In 1954, a new company, "San Ferdinando Film", ran a six show series of the Il Teatro di Eduardo and De Filippo continued to work in cinema to pay for theatre restoration.
[12] In its prime in the late 1950s, the theatre featured actors such as Enzo Cannavale, Ettore Carloni, Gennarion Palumbo, Pietro Carloni, Lello Grotta, Enzo Petito, Pietro De Vico, Cilelia Matania, Graziella Marina, Pupella Maggio, Antonio Casagrande, Angela Pagano, Anna Maria Colonna, Nina De Padova, Riccardo Grillo, Vittorio Ardesi, Giorgio Manganelli, Liana Tronche, Maria Hilde Renzi, Andrea Biello, Olga D' Ajello, Scilla Vannucci, and Nico Da Zara.
In 1964, the theatre became the "Teatrale Napoletana", a company founded by Paolo Grassi and Giorgio Strehler, founders and owners of the Piccolo Teatro di Milano.
On 30 September 2007, after many years of restoration and large investments, the San Fernando reopened its doors with Shakespeare's The Tempest, in the translation made by Eduardo De Filippo in 1984.