Telmatobius mayoloi is a species of frog in the family Telmatobiidae.

Its natural habitats are subtropical or tropical high-altitude grassland and rivers.

Telmatobius mayoloi, including the tadpoles, are used for food and medicine.

[1] Telmatobius mayoloi have been significantly declining in the past recent years.

They are also expected to continue declining in population for the next 10 years.