Previously, Amtrak's Sunset Limited and Texas Eagle trains stopped at the station, but they were shifted to a more southerly route in June 1996.

The station was served by Amtrak's Sunset Limited and Texas Eagle from 1987 until June 3, 1996, when Amtrak was forced to re-route the trains due to deteriorated track conditions on the secondary Union Pacific Railroad line which diverged from the mainline to serve Phoenix and Tempe.

Amtrak opened the Maricopa station to serve Phoenix, Tempe and the greater Central Arizona area.

In Spring 2022, the Tempe Streetcar is expected to open, with southbound cars passing right by the station site.

[1] As of 2023[update], Amtrak is planning to restore train service to Tempe on a route between Phoenix and Tucson.