Ten Mile Run is an unincorporated community and census-designated place (CDP) located in Franklin Township, in Somerset County, in the U.S. state of New Jersey.

Most of the area consists of less densely-spaced single family homes throughout and commercial establishments along Route 27.

The remainder of the area is forested and hilly as the terrain descends towards the Delaware and Raritan Canal and Millstone River.

Kendall Park, the CDP located on the South Brunswick side of Route 27, consists of more densely-spaced homes.

[12] The 2010 United States census counted 1,959 people, 602 households, and 514 families in the CDP.