It continues east through rural unincorporated Robertson County, near Cross Plains, to intersect and have a short concurrency with SR 49, before separating and continuing east, becoming a primary highway.

It continues into downtown Gallatin to intersect and run concurrently with SR 174/SR 386.

Just before the county line, SR 25 passes just north of the abandoned Hartsville Nuclear Plant.

Continuing into Carthage, it intersects with SR 263, providing access to downtown.

Currently, a project to modify the intersection with SR 49 east of Springfield is underway.