State Route 319 (SR 319) is a state highway in southeast Tennessee, starting at the intersection of SR 153 in Chattanooga, traveling to the area of Soddy-Daisy where it intersects with US 27, and the route comes to an end.

SR 319 then turns north as DuPont Parkway to have an interchange with Access Road and Hixson Pike.

It again interchanges and becomes concurrent with Hixson Pike, turning northeast and leaving Chattanooga/Hixson 3.7 miles from SR 153.

SR 319 then enters the community of Middle Valley and after 3.3 miles it leaves Middle Valley corporate limits and enters the city of Lakesite.

After it leaves Lakesite it passes the Sequoyah Nuclear Plant, turns northwest and enters Soddy-Daisy city limits to end at US 27/SR 29.