It begins at US 11E/US 321 in Greeneville and ending at the Tennessee–Virginia state line in Bloomingdale, Tennessee.

The route intersects SR 81 just south of Fall Branch and heads more northerly.

In Fall Branch, it has an interchange with I-81 exit 50 and continues north to Kingsport where it intersects SR 347 just south of there.

The route heads east as a controlled-access southern bypass of the city passing by Eastman Chemical Company and crossing over the South Fork Holston River and has an interchange with SR 36.

SR 93 then turns back north to an interchange with US 11W and then it meets its northern terminus, at the Tennessee–Virginia State Line in Bloomingdale.