Osteocephalus exophthalmus Smith & Noonan, 2001 Tepuihyla exophthalma is a species of frog in the family Hylidae.

Its eyes are described as "large and bulgy" and "huge and protruding" and inspired the specific epithet exophthalmus.

They are buff with a black cross shape across the iris; this eye coloration is a main feature that distinguishes the species from other frogs in the genus.

The skin is mostly smooth with a few tubercles along the dorsal surface and a granular texture to the throat and belly.

[3] After the first specimen was recorded, the species was also discovered living in Guyana's Kaieteur National Park and across the border in Estado Bolívar, Venezuela.