Terence S. Dermody

Terence S. Dermody is an American virologist who is the Vira I. Heinz Distinguished Professor and Chair of Pediatrics at the University of Pittsburgh School of Medicine, where he teaches microbiology and infectious diseases.

In 1990, Dermody joined Vanderbilt University School of Medicine, where he was the Dorothy Overall Wells Professor of Pediatrics.

[11] Dermody studies fundamental mechanisms of viral replication to better understand the propagation of viruses and the cause of disease.

By understanding how viruses behave, he hopes to find ways to fight them and develop new vaccines.

As an example of this work, in 2011, Dermody identified the protein kinase Src as a mediator of reovirus cell entry.

[14] In 2017, a collaboration between Bana Jabri and others at the University of Chicago Celiac Disease Center and Dermody's group suggested that reovirus infection triggers the immune system to respond to gluten in a way that later leads to celiac disease.

[16] Dermody also studies chikungunya virus,[2][17] a potentially deadly mosquito-borne infection that is spreading to new areas because of changes in climate.

The reovirus replication cycle. VI—viral inclusions; ER—endoplasmic reticulum. [ 12 ]