Initially, quid was a disparaging term that referred to cross-party coalitions of Federalists and moderate Republicans, such as those who supported the election of Thomas McKean as governor of Pennsylvania in 1805.
Between 1801 and 1806, rival factions of Jeffersonian Republicans in Philadelphia, Pennsylvania, engaged in intense public debate and vigorous political competition, which pitted radical Democrats against moderate ones, who defended the traditional rights of the propertied classes.
The radicals, led by William Duane, the publisher of the Jeffersonian Aurora, agitated for legislative reforms that would increase popular representation and the power of the poor and the laboring classes.
The New York State and the Pennsylvania Quid factions had no connection with each other at the federal level, and both of them supported US President Thomas Jefferson.
After Randolph failed to impeach a Supreme Court justice in 1805, he became embittered with Jefferson and Madison and complained: "Everything and everybody seem to be jumbled out of place, except a few men who are steeped in supine indifference, whilst meddling fools and designing knaves are governing the country.