Tetanolysin is a toxin produced by Clostridium tetani bacteria.
Its function is unknown, but it is believed to contribute to the pathogenesis of tetanus.
The other C. tetani toxin, tetanospasmin, is more definitively linked to tetanus.
Tetanolysin belongs to a family of protein toxins known as thiol-activated cytolysins, which bind to cholesterol.
[2] Cytolysins form pores in the cytoplasmic membrane that allows for the passage of ions and other molecules into the cell.