Introduced in the 1980s by American Cyanamid, the molecule features two isocyanate groups.

It is produced by the reaction of diisopropenylbenzene with hydrogen chloride followed by isocyanic acid:[4] A key use for TMXDI is in manufacturing polyurethane prepolymers.

This difference increases cost.When making polyurethanes dispersions (PUDs) TMXDI is advantageous.

Being sterically hindered, the NCO groups are slower reacting which is good when dispersing a prepolymer in water to make a PUD.

It reduces side reactions and allows more time to allow the dispersion stage before the mix is chain extended.