The highway is named for Harry M. Wurzbach, who represented the San Antonio area in Congress as a Republican in the 1920s and 1930s.

From Wetmore Road, on the northeast side of the San Antonio International Airport, the parkway continues east beyond Thousand Oaks Drive.

The road, estimated to cost $90 million,[5] was approved by the Texas Transportation Commission in 1988, to be built by the state but funded in part by the City of San Antonio.

[10] The Alamo Regional Mobility Authority (RMA) conducted a supplemental environmental assessment on the entire corridor from Lockhill–Selma Road to I-35, emphasizing the segment that had not been constructed.

[14] According to the San Antonio Express-News, the Texas Transportation Commission reviewed the parkway expansion on November 19, 2009.

TxDOT has also proposed improvements to the parkway's intersections at NW Military Highway and Lockhill-Selma Road.