State Highway 273 (SH 273) is a state highway that runs from Pampa in northern Texas east and south to SH 203 near Hedley.

The route was originally designated on July 30, 1938 from Pampa to McLean.

[2] On November 4, 1971, an extension along Ranch to Market Road 2695 to US 287 along was signed, but not designated.

After a brief co-routing with Loop 171, the highway runs southeast to Lefors and then south to a junction with Interstate 40 at McLean, where the route is known as Sitter Street.

Most of the terrain covered by the highway is lightly populated ranch and oil country.