The next use of the Loop 405 designation was in Walker County, from SH 19 northeast of Huntsville southward to I-45.

[6] Loop 406 was designated on April 1, 1965, from then-new US 90 north along old US 90 across Devils River to US 90.

On October 27, 1967, the section from 0.7 miles (1.1 km) northwest of US 90 to a point 9.4 miles (15.1 km) northwest was removed altogether, the section from the southeast junction with US 90 to a point 0.7 miles (1.1 km) northwest was transferred to Spur 454 and the remainder was changed to Spur 406.

[14] Loop 415 was designated on September 1, 1965, from US 77/US 83 in Brownsville along an old routing of US 77/US 83 to the Gateway Bridge at Elizabeth and 14th Streets.

It runs north along Main Street, intersecting Buffington Lane in a traffic circle around the county courthouse, before continuing to its northern terminus at FM 149.

The remainder of Loop 436 was cancelled on September 25, 1989, and removed from the highway system.

On June 21, 1990, Loop 448 was cancelled: the Raymondville-Sebestian section was transferred to Bus.

Loop 452 was designated on April 8, 1986, in Gatesville, from SH 36 south 3.4 miles (5.5 km) to US 84 and from US 84 southeast 1.1 miles (1.8 km) to SH 36, creating a concurrency with US 84.

On December 15, 1981, the route was modified to run continuous along city streets.

The road continues northeastward to its eastern terminus at a T intersection with SH 204.

[46] A later plan to extend the route from US 79 east of downtown Jacksonville to the north side of the city at US 69 was not implemented or built.

The route travels along Loop Road to the north and enters the city as it crosses over I-20; access from the freeway is provided by exit 79.

The highway passes between Thorntonville to the west and Roy Hurd Memorial Airport to the east before crossing Business I-20, the former route of US 80 through the city.

Loop 464 turns to the northwest and leaves the city limits before resuming a more northerly trajectory and ending at another junction with SH 18.

[53] As of November 2012[update], TxDOT is considering the addition of a ramp along eastbound I-20 at the exit for Loop 464.

After the two routes separate, Loop 467 intersects RM 1691 before turning back to the northeast and leaving Sonora.

Its southern terminus of Loop 478 is at US 62 (East Paisano Drive) in El Paso near the Bridge of the Americas.

The route travels north along Copia Street, intersecting SH 20 (Alameda Drive) and crossing under the I-10 freeway at its exit 22A.

It then turns northwest onto Pershing Drive and then north on Dyer Street, paralleling US 54 (Patriot Freeway) to its east.

[64][65] Loop 478 was established on April 2, 1969, from US 54 near the New Mexico state line to the Mexican border along the Rio Grande.

Beginning near the Eagle Pass Camino Real Port of Entry, it runs counterclockwise, crossing FM 1021 and US 277, before ending at US 57 northwest of the city.

The Loop 480 designation extends past the current northern terminus to another intersection with US 277 north of Eagle Pass; however, as of 2022[update], this segment has not been constructed.

A previous route numbered Loop 480 was designated in Lamar County on May 28, 1969,[72] from US 82 in northern Paris south and southeast 4.9 miles (7.9 km) to US 271.

The highway travels in an eastern direction along Main Street and passes through the Junction town square.

Loop 481 turns in a southeast direction at East Main Street and crosses the South Llano River before leaving the town.

The highway has a short overlap with FM 2169 near the Texas Tech University Junction Center.

The highway travels through rural areas and hilly terrain before ending at an interchange with I-10 / US 83.

[citation needed] Loop 484 was designated on September 25, 1984, along the current route.

It runs counterclockwise around the southern and eastern portion of the city, crossing US 80, before reaching its northern terminus at another junction with US 271.

Loop 496 was designated on December 17, 1970, from US 81/US 287 south of Avondale to I-820 (now I-20) in Fort Worth along an old routing of US 81/US 287.