[1] Spur 536 begins at the intersection of US 281 and Loop 410; northbound US 281 follows Loop 410 to the east, while Spur 536 continues north along Roosevelt Avenue through the mission district of San Antonio.

[2] The route passes the west side of Stinson Municipal Airport before crossing Loop 13 (Military Drive).

It then turns west along Alamo Street before ending at I-10/35.

[1] Spur 536 was proposed for decommissioning in 2014 as part of TxDOT's San Antonio turnback proposal, which would have turned back over 129 miles of roads to the city of San Antonio, but the city of San Antonio rejected that proposal.

[4] The entire route is in San Antonio, Bexar County.