It is known for animating notable works such as Marvelous Melmo, the 1980 and 2003 Astro Boy series, and Black Jack.

Their logo is a blue silhouette of Astro Boy's head as a mascot.

[4] For the first few years, the studio took sub-contracted animation work from Mushi Production, which included a variety of animated shorts and a full television series, Fushigi na Merumo (Marvelous Melmo), which was broadcast by TBS for 26 episodes from October 1971 to March 1972.

[4] From 1980 to 1981, Tezuka Productions produced a remake for Astro Boy that ran for 52 episodes on Nippon TV.

[9] The film was completed in 2014, premiering at the 2014 Hiroshima International Animation Festival in August, and in North America at the Japan Society in New York City on February 21, 2015.