Thabo Makhetha studied at the Nelson Mandela Metropolitan University in Port Elizabeth where she graduated with a National Diploma in Fashion.
[3] Thabo Makhetha made her runway debut in 2014 at Vancouver Fashion Week in Canada,[4] where she was praised for the quality and creativity of her work for the Kobo ea Bohali "Blanket of Prestige" collection.
In 2016 then editor of Elle Magazine nominated Thabo's starburst coat for Most Beautiful Object in South Africa.
In 2017, Louis Vuitton caused headlines by producing a men's collection using a similar print as Basotho blanket, a controversial move that sparked accusations of cultural appropriation.
[9][10] Thabo Makhetha-Kwinana took part in artist-in-residence programme of the exhibition: “Breaking Down the Walls" – 150 years of collecting at Iziko South African Museum, which commemorated Africa Day on 25 May 2023.