Promoted to the first team in 2013, he made his senior debut on 20 January of that year by starting in a 0–4 Campeonato Pernambucano home loss against Central.

[5] On 29 June 2017, Thaciano returned to his parent club after an agreement between Santos and Boa Esporte was not reached; he only represented the main squad once, in a friendly against KAC Kénitra.

On 29 November 2017, after scoring a career-best ten goals, Thaciano agreed to a two-year loan deal with Grêmio, with a buyout clause.

[7] On 7 May 2019, he was bought outright by the club for a fee of R$ 2 million for 80% of his federative rights, and signed a three-year contract.

[10] On 16 July, however, he moved abroad and joined Süper Lig side Altay also in a temporary deal.