Thakin Soe (Burmese: သခင်စိုး, pronounced [θəkʰiɰ̃ só]; 1906 – 6 May 1989) was a founding member of the Communist Party of Burma and a leader of the Anti-Fascist Organisation.

[3] Communist leaders Thakin Than Tun and Thakin Soe, and Socialist leaders Ba Swe and Kyaw Nyein and the Burma National Army (BNA) led by General Aung San founded the Anti-Fascist Organisation (AFO) in August 1944 at a secret meeting of the CPB, the PRP and the BNA in Pegu.

[4] Thakin Than Tun and Thakin Soe, while in Insein prison in July 1941, had co-authored the Insein Manifesto which, against the prevailing opinion in the Dobama movement, identified world fascism as the main enemy in the coming war and called for temporary co-operation with the British in a broad allied coalition which should include the Soviet Union.

[4] Thakin Soe spent most of his life underground and for a time led the Red Flag Communist Party.

After nationwide demonstrations against Ne Win's government in 1988, Soe re-entered the politics in August 1988 and became the patron of the Unity and Peace Party in September 1988, which he hoped would contest in the 1990 elections.