The $1,000,000 Chance of a Lifetime is an American game show which offered a $1 million (annuitized) grand prize to winning contestants.

The show was hosted by Jim Lange, and he was joined by Karen Thomas as co-host during the second season.

Once a contestant guessed correctly, he/she stepped up to an oversized keyboard to place letters in the puzzle, which was displayed on a giant computer screen.

In the second round, the couples switched positions and the values for each word and correctly placed letter doubled to $50.

Once they made the selection, the show's on-stage security guard led them into an isolation booth which was wired so they could only hear Lange and could only see the game board screen.

For the second season, the couple received over $900,000 as an annuity and an additional $100,000 in prizes, including a pair of automobiles and 20 round-trip tickets on Delta Air Lines valid for any destination in the continental United States.

If at any time the couple failed to win the bonus round, they were retired as champions and left with whatever they had won in the main game to that point.