The Adventures of Barry Ween, Boy Genius is a comic book metaseries created, written and illustrated by Judd Winick.

It follows the comical escapades of the eponymous character, a 10-year-old boy who secretly possesses the most powerful intellect on Earth, along with his impulsive best friend Jeremy and his crush Sara.

Many of the storylines involve one of Barry's inventions going horribly wrong (usually due to Jeremy's clumsiness) and the two boys' efforts to right the situation before anyone can find out.

For a time Winick's website listed Barry Ween: Boy Genius in Space as an upcoming work, which after being on hiatus for 8 years has recently been announced to be in progress.

He is an extremely prolific inventor and has built an immense secret lair underneath his suburban home full of robots, futuristic transports, and weapons.

Despite his genius, however, Barry is prone to making errors in his experiments that can lead to near-catastrophic consequences, like turning his aunt into an enormous deformed blob, knocking the Earth out of the Sun's orbit, or accidentally creating an inter-dimensional rift in his basement.

Despite the great power that his intelligence grants him, he admits later in the series that his superior mind is a kind of curse: he cannot stop thinking, calculating probabilities, and formulating plans; so he never sleeps.