The Alphabet Versus the Goddess: The Conflict Between Word and Image is a work of historical anthropology by American surgeon Leonard Shlain, published by Viking Press in 1998.

Shlain began with the insight: "when a critical mass of people within a society acquire literacy, especially alphabet literacy, left hemispheric modes of thought are reinforced at the expense of right hemispheric ones, which manifests as a decline in the status of images, women's rights, and goddess worship.

Sandra Blakeslee writes in The New York Times, “The human nervous system, he says, was substantially rewired when people began reading alphabets.

[Brain researchers] now know that the left and right halves of our brains interact dynamically and that specialization, which undoubtedly exists, is a matter of processing style rather than having specific mental traits reside on one side or the other.” [2] Other critics focus on a perhaps inevitable consequence of Shlain's wide-ranging application of his paradigm: errors of fact.

Kirkus Reviews calls the book, “Continually engaging, although on the whole quite woolly.”[4] “This is one of those annoying books, in which I find some bits gripping and enlightening, and other bits simply untenuously presumptuous…"[5] Several reviewers have commented that the book is readable and engaging: "And yet, having put all my reservations on the table, I am still left with a good feeling about some parts of the book.”[5] George Steiner writes in The Guardian, "Whatever Schlain's competence, there is so much in The Alphabet versus The Goddess that is slapdash and amateurish...None the less, this is a stimulating read, and the central notion that women have not been fully welcome or at home in western civilisation is, ambiguously, seductive.