The brewpub is located at 3525 Liberty Avenue in the Lawrenceville neighborhood of Pittsburgh, Pennsylvania.

[1] Its doors opened as The Church Brew Works on August 1, 1996, after the building underwent extensive renovation, necessitated by years of lying dormant after being officially deconsecrated by the Diocese of Pittsburgh in 1993.

[2] As of September 2007, three flagship brews are locally distributed: Celestial Gold (light lager), Pipe Organ Pale Ale (English pale ale), and Pious Monk Dunkel (Munich-style dark lager).

The in-house selection is rounded out by a rotating Stout, four seasonals or specialties, and one varying cask-conditioned ale.

In 2012 the Church Brew Works won the Great American Beer Festival's Large Brewpub Brewer of the Year Award.