Journalist Mike Harway decides to help his friend Christine Becker in her search for her father, professor Baker.

Mike, Christine and Professor Baker make a desperate attempt to escape from the fortress before the transfer occurs.

The Devil's Man was the first of three films director Paolo Bianchini directed for producer Gabriele Crisanti.

[1] Crisanti stated that the film was designed to recover costs and recycle scenes from his other production I predoni del Sahara (1965) directed by Guido Malatesta.

"[3] In Phil Hardy's book Science Fiction, The Devil's Man was referred to as a "routine mad scientist offering.