The film stars Mark Kelly, Steve Zissis, Jennifer Lafleur, and Julie Vorus.

[3] The film is about two brothers in their mid-30s (played by Mark Kelly and Steve Zissis) whose lifelong rivalry compels them to secretly complete an athletic competition that they came up with in high school but left unfinished.

[6] Shortly after, it was announced that Fox Searchlight Pictures, and Red Flag Releasing had acquired distribution rights to the film.

The website's critics consensus reads: "Slight but satisfying, The Do-Deca-Pentathlon wrings fresh laughs from tired man-child comedy tropes.

"[8] Critic Stephen Holden of The New York Times called it the Duplass brothers' second-best film, after their debut, The Puffy Chair.