The God of the Machine is a book written by Isabel Paterson and originally published in January 1943 in the United States by G. P. Putnam's Sons.

[6] Isabel Paterson wrote a regular column for the New York Herald Tribune, where she first articulated many of her beliefs, which reached their final form in The God of the Machine.

Paterson opposed most parts of the economic program known as the New Deal that US president Franklin D. Roosevelt and the Congress put into effect during the 1930s and she advocated less governmental involvement in social and fiscal matters.

She also led a group of younger friends (many of whom were other employees of the Herald Tribune) who shared her views.

Paterson and Rand promoted each other's books, and they conducted an extensive exchange of letters, touching on religion and philosophy.