The Greyhound was a pub (popularly known as "The Spotted Dog"), in High Street, Old Portsmouth, England.

It became a private building called Buckingham House and was listed under that name in 1953.

The murder site was toured by the diarist and Royal Navy administrator Samuel Pepys in 1662.

Pepys was accompanied by his wife Elisabeth, along with his Republican clerk Tom Hayter and wife, and the Earl of Sandwich's Puritan secretary John Creed (Pepys' Diary, 3 June).

[2] The building bears a commemorative plaque to mark the assassination.