The Kerouac Project began with a chance discovery by Bob Kealing, a reporter with the Orlando area NBC affiliate and freelance writer.
In 1996 he learned that Jack Kerouac had been living in a c. 1920 Orlando cottage when his classic work On the Road was published to worldwide acclaim in 1957 and where he actually typed the original manuscript of his later novel, The Dharma Bums.
The Project currently owns an editor's copy of this manuscript with Kerouac's hand written notes and it is retained at the Olin Library at Rollins College.
In October 2008, several students from Full Sail University produced a video about the house and its history.
In September, 2013, a fundraiser was held for the organization at the Cornelia Street Cafe in New York City, which featured composer David Amram, author Joyce Johnson and actors Michael Shannon and John Ventimiglia.