Loosely based on the 1886 novella Strange Case of Dr Jekyll and Mr Hyde by Robert Louis Stevenson,[2] the film's plot concerns an insane killer with dual personalities who stalks and murders victims at a nursing academy.

It stars Sebastian Brook, Mady Maguire, Donn Greer, Gray Daniels, John Terry, and Rene Bond.

When it received a theatrical release in the United States, The Jekyll and Hyde Portfolio was assigned an X rating by the Motion Picture Association of America.

"[3] In his book Nightmare USA: The Untold Story of the Exploitation Independents, Stephen Thrower called the film an "awful but entertaining cheapie".

[4] Brian Orndorf of Blu-ray.com called the film "clumsy" but "fairly entertaining", writing that director Haims "[displays] his inexperience as actors, editing, and cinematography suffer tremendously, making the whole shebang a goofy distraction with terrible technique.