The Killing Room

The Killing Room is a 2009 psychological thriller film directed by Jonathan Liebesman and starring Clea DuVall, Nick Cannon, Chloë Sevigny and Timothy Hutton.

[2] Four individuals sign up for a psychological research study only to discover that they are now subjects of a brutal, modern version of the Project MKULTRA indoctrination program.

Upon completing his introduction, the researcher shoots the female subject in the head with a gun and promptly leaves the room.

It is revealed, during the last subject's escape attempt, that the goal of the covert program is to achieve in human civilians a phenomenon similar to apoptosis in cells (a comparison noted in the film), by developing "civilian weapons" akin to suicide bombers.

[3] MTV's Larry Carroll labeled it as the “best movie” at Sundance 2009, praising it as “brutal, daring and utterly unpredictable”.