In 1967, EIC Jesus Manalastas opens Guest Writer, a column space for editors of student publications outside De La Salle College.

From 1972 to 1973, EIC Calixto Chikiamco, rumored to be the leader of the League of Filipino Students, introduced a Filipinization of the publication by tackling, among other topics, nationalism, radicalism, Communism, and Maoism.

As De La Salle College became co-educational during this period, Irmina Nobleza and Josefina Sayoc became the first female writers of The LaSallian.

In 1983, frustrated by what it saw as Lasallian indifference, the publication releases a special issue detailing the active participation of UP and Ateneo in the opposition movement against President Ferdinand Marcos.

TLS' October 1983 editorial, Manila on the March, details the outpouring of anger against the Marcos administration in the aftermath of Benigno Aquino's assassination.

TLS, in response to the UAAP Board's decision to forfeit its championship win against the Far Eastern University Tamaraws’ men's basketball team, publishes its shortest editorial to date: “80-77.

A series of deaths related to the university's Reserve Officers' Training Corps hit campus, prompting an official investigation which led to the expulsion of more than 20 students.

An inquiry by EIC Luis Laparan and University (News) Editor Edwin Tumbagan in 1995 leads to the closure of several establishments serving alcoholic drinks and allowing the play of billiards.

In 2005, EIC Paul Garilao and University Editor Donelle Gan expose the exploits of a sexually harassing faculty member.

In 2006, under EIC Donelle Gan, TLS details the formation of De La Salle Philippines, the newly formed overseeing body of all Lasallian schools in the country.

Armin Luistro FSC accepts the Department of Education secretary post and TLS is first to report about the changes in DLSU leadership.

In 2011, the community celebrates 100 years of Lasallian presence in the Philippines and TLS releases a Centennial Issue in commemoration under EIC Jessy Go.

Art & Graphics Editor Jerome de Dios leads the redesign and standardization of the broadsheet layout and the masthead font changes from Times New Roman to Arno Pro.

[5] In 2014, The LaSallian was named the third best Four-year Non-weekly Newspaper by the United States-based Associated Collegiate Press (ACP) at the 2014 Best of the Midwest Best of Show awards.

In 2017, TLS 57 provided live coverage of the Lasallian initiatives and protests against the Marcos Burial in the Libingan ng mga Bayani.

[8] During SY 2007-2008, The LaSallian and Ateneo de Manila University's official newspaper, The GUIDON, started an annual student press convention called PressPlay in cooperation with the National Union of Journalists of the Philippines (NUJP).