The show began broadcasting in January 2016, originally on the STV Glasgow and STV Edinburgh networks,[1] until both channels were axed in 2017 and merged to form the new STV2 channel, where the programme aired at 10:30 pm.

[2] On 16 May 2018, it was announced that STV2 would close and all of its original programming including The Late Show with Ewen Cameron would be axed in June 2018.

When first broadcast, The Late Show shared a studio and set equipment with that of Live at Five which was being broadcast on STV Glasgow, the only differences being the names were changed at the back of the set from Live at Five to The Late Show.

The programme featured regular sketches which involve Cameron interacting and talking with members of the public.

The format of interviewing guests are again very similar to that of other late night talk shows, where the guests sat to the right of Cameron, but left to the viewing audience, whilst Cameron sat behind a desk with a laptop and a microphone situated on the desk.