The season was won by singer Ne-Yo as "Cow", with actor/singer John Schneider finishing second as "Donut", actress/singer Janel Parrish placing third as "Gazelle", and singer Macy Gray placing fourth as "Sea Queen".

Nick Cannon, singer-songwriter Robin Thicke, television and radio personality Jenny McCarthy Wahlberg, actor and comedian Ken Jeong, and recording artist Nicole Scherzinger all return as host and panelists for their tenth consecutive season.

[1] The first episode included David Spade as an additional guest, the second episode included Le'Veon Bell ("Milkshake" from season eight), Antonio Gates, and DeSean Jackson as additional guests, the third episode included season six winner Jewel, Lance Bass, and Kate Flannery as additional guests, the fifth episode included season two finalist Adrienne Bailon-Houghton as an additional guest, the seventh episode included Trolls characters Queen Poppy and Branch as additional guests, the eighth episode included The Trammps and Taylor Dayne ("Popcorn" from season four) as additional guests, the ninth episode included Kelly Osbourne ("Ladybug" from season two) and Bret Michaels ("Banana" from season three) as additional guests, and the tenth episode included Hunter Hayes ("Astronaut" from season three) as an additional guest.

[2] A promo revealing the season's premiere date featured letters inspired by previous costumes.

[3] A special preview episode aired on September 10, and featured previous contestants such as Michelle Williams and Rumer Willis, Joey Fatone and Bow Wow, and Victor Oladipo and Barry Zito, as well as a special unmasking.