Nick Cannon, singer-songwriter Robin Thicke, television and radio personality Jenny McCarthy Wahlberg, actor and comedian Ken Jeong, and recording artist Nicole Scherzinger all returned as host and panelists.

During production, it was reported that 12 positive cases of COVID-19 were confirmed at Red Studios Hollywood, though filming was not halted.

Ken Jeong pushed the button for Group A and incorrectly guessed that "Pepper" was Sara Bareilles, while Jenny McCarthy Wahlberg pushed the button for Group B and incorrectly guessed that "Caterpillar" was Jake Gyllenhaal.

For the first time in the show's history, the winner of each group will face-off against each other in the season finale episode.

Fox ("Mother Nature"), Toni Braxton ("Pufferfish"), Tyga ("Dalmatian"), Larry the Cable Guy ("Baby"), Ruth Pointer ("Cupcake"), Rob Schneider ("Hamster"), Johnny Rotten ("Jester"), Natasha Bedingfield ("Pepper"), Willie Robertson ("Mallard"), Bobby Berk ("Caterpillar"), Faith Evans ("Skunk"), David Foster & Katharine McPhee ("Banana Split"), Todrick Hall ("Bull"), and Jewel ("Queen of Hearts") Guest panelist performance: "This Little Light of Mine" performed by Leslie Jordan as "Soft Serve"